C-Morphine was prepared by methylation of normorphine with CH31. Acetylation of this compound yields heroin. The radiochemical yield is 9% for morphine and 4 % for heroin at a specific activity of 1.63 mCi/pmole. Synthesis time including purification by hplc is 18 min for "C-morphine and 36 min for
[N-methyl-11C]-scopolamine: Synthesis and distribution in rat brain
✍ Scribed by Manhar M. Vora; Ronald D. Finn; Thomas E. Boothe; David R. Liskwosky; Lincoln T. Potter
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- French
- Weight
- 304 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract [^11^C]Paraquat was synthesized by the reaction of [^11^C]methyl triflate with the mono‐triflate salt of 1‐methyl‐[4,4′]bipyridinyl. The product was selectively separated from the precursor by a microcolumn of Chelex 100 ion exchange resin. The method was applied to the synthesis of a v
Local cerebral serotonin synthesis capacity was measured with ␣- [C-11]methyl-L-tryptophan ([C-11]AMT) in normal adult human brain (n ϭ 10; five males, five females; age range, 18-38 years, mean 28.3 years) by using positron emission tomography (PET). [C-11]AMT is an analog of tryptophan, the precur
## Abstract Three ^11^C‐labelled tracers for the serotonin reuptake site, __S__‐[__N__‐methyl‐^11^C]citalopram (**[^11^C]‐4**), __S__‐[__N__‐methyl‐d~3~‐^11^C]citalopram (**[^11^C]‐12**), and __S__‐[__N__‐methyl‐^11^C]citalopram‐α,α‐d~2~ (**[^11^C]‐13**) were synthesized and the distribution of rad
## Abstract A method for labelling 6,7‐dichloro‐2,3‐dihydroxyquinoxaline (DCQX) in position 2 with carbon‐11 is presented. Diethyl [1‐^11^C]oxalate was synthesized in a two‐step, microwave‐assisted procedure from no‐carrier‐added [^11^C]cyanide and was reacted with 4,5‐dichloro‐1,2‐phenylenediamine