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N-halo derivatives III: Stabilization of nitrogen-chlorine bond in N-chloroamino acid derivatives

✍ Scribed by James J. Kaminski; Nicolae Bodor; Takeru Higuchi

Book ID: 102914278
Publisher: John Wiley and Sons
Year: 1976
Tongue: English
Weight: 557 KB
Volume: 65
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600650418

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✦ Synopsis

The chlorination of a-amino acids and their related derivatives was investigated. A kinetic study of the stability of these N-chlorinated products led to an elucidation of the factors that significantly influence the stability and reactivity of the nitrogen-chlorine bond in these N-chloramines. From the kinetic investigations, a series of low chlorine potential, soft antimicrobial Nchloramines was developed based on derivatives of a-aminoisobutyric acid and related compounds.

Keyphrases 0 N-Chloroamino acid derivatives-synthesis, kinet-

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