Hydrolysis of N-Terminal Peptide Bonds and Amino Acid Derivatives by the β-Hydroxoaquotriethylenetetraminecobalt(III) Ion
✍ Scribed by Buckingham, David A.; Collman, James P.; Happer, Duncan A. R.; Marzilli, Luigi G.
- Book ID
- 126481610
- Publisher
- American Chemical Society
- Year
- 1967
- Tongue
- English
- Weight
- 767 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0002-7863
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Comparison of the acetyl-, trifluoroacetyl-, benzyloxycarbonyl-, rnethoxycarbonyl-, ethoxycarbonyl, methylaminocarbonyl, phenylaminocarbonyl-, phthaloyl-and stearoyl-derivatives of glycyileucylphenylalanine rnethyl ester has shown that the acetyl derivative is the most volatile. The relative abundan
## Abstract L‐Aspartic acid by tosylation, anhydride formation, and reduction with NaBH~4~ was converted into (3__S__)‐3‐(tosylamino)butan‐4‐olide (8; __Scheme 1__). Tretment of 8 with ethanolic trimethylsilyl iodide gave the __N__‐protected deoxy‐iodo‐β‐homoserine ethyl ester 9. The latter, on suc