N-acetyltransferase 2 (NAT2) genotypes, cigarette smoking, and the risk of breast cancer
β Scribed by Anthony J Alberg; Alexander Daudt; Han-Yao Huang; Sandra C Hoffman; George W Comstock; Kathy J Helzlsouer; Paul T Strickland; Douglas A Bell
- Book ID
- 113524229
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 81 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0361-090X
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Although inconsistencies exist, some studies have shown that meat consumption is associated with breast cancer risk. Several heterocyclic amines (HAs), formed in the cooking of meats, are mammary carcinogens in laboratory models. HAs are activated by polymorphic N-acetyltransferase (NAT2) and rapid