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N-acetyltransferase-2 gene polymorphisms and prostate cancer susceptibility in Latin American patients

✍ Scribed by Mario Maciel de Lima Junior, Leonardo Oliveira Reis, Ana Carolina Trindade Guilhen, Fabiana Granja, Mariana Nicolau de Lima Oliveira, Ubirajara Ferreira, Lucas Leite Cunha, Laura Sterian Ward

Book ID
118821555
Publisher
Springer US
Year
2012
Tongue
English
Weight
183 KB
Volume
29
Category
Article
ISSN
1357-0560

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The acetylation polymorphism is a common inherited variation in human drug and carcinogen metabolism. Because Nacetyltransferase (NAT2) is important for the detoxification and/or bioactivation of drugs and carcinogens, polymorphisms of this gene have important implications in therapeutics of and sus