N-Acetyltransferase 2 Polymorphisms, Tobacco Smoking, and Breast Cancer Risk in the Breast and Prostate Cancer Cohort Consortium
โ Scribed by Cox, D. G.; Dostal, L.; Hunter, D. J.; Le Marchand, L.; Hoover, R.; Ziegler, R. G.; Thun, M. J.; Diver, W. R.; Stevens, V. L.; Amiano, P.; Boutron-Rualt, M.-C.; Campa, D.; van Duijnhoven, F. J. B.; Gram, I. T.; Kaaks, R.; Khaw, K.-T.; Riboli, E.; Sund, M.; Trichopoulos, D.; Tumino, R.; Vogel, U.; Kraft, P.; Buring, J. E.; Hankinson, S. E.; Lee, I.-M.; Zhang, S. M.; Lindstrom, S.; Berg, C. D.; Chanock, S.; Isaacs, C.; McCarty, C.; Haiman, C. A.; Henderson, B. E.
- Book ID
- 121795758
- Publisher
- Oxford University Press
- Year
- 2011
- Tongue
- English
- Weight
- 99 KB
- Volume
- 174
- Category
- Article
- ISSN
- 0002-9262
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Although inconsistencies exist, some studies have shown that meat consumption is associated with breast cancer risk. Several heterocyclic amines (HAs), formed in the cooking of meats, are mammary carcinogens in laboratory models. HAs are activated by polymorphic N-acetyltransferase (NAT2) and rapid