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N-Acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats

✍ Scribed by N Chen; K Aleksa; C Woodland; M Rieder; G Koren

Book ID
109838940
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
326 KB
Volume
153
Category
Article
ISSN
0007-1188

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Nephrotoxicity of ifosfamide in rats
Nephrotoxicity of ifosfamide in rats
✍ James E. Springate; Judith B. van Liew πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 405 KB πŸ‘ 1 views

Renal proximal tubule cell injury is an important side effect of the chemotherapeutic agent ifosfamide in humans. We investigated the effect of this medication on kidney function in rats. Animals received either 40 or 80 mg kg-' ifosfamide intraperitoneally daily for 3 days every 3 weeks for a total