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Melatonin prevents acetaminophen-induced nephrotoxicity in rats

✍ Scribed by Yusuf Özlem İlbey; Emin Ozbek; Mustafa Cekmen; Adnan Somay; Levent Ozcan; Alper Otünctemur; Abdulmuttalip Simsek; Fatih Mete

Publisher
Springer Netherlands
Year
2009
Tongue
English
Weight
292 KB
Volume
41
Category
Article
ISSN
0301-1623

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## Abstract The aim of the study was to analyze the impact of melatonin on brain oxidative stress in experimental biliary obstruction. Cholestasis was done by a double ligature and section of the extrahepatic biliary duct. Melatonin was injected intraperitoneally (500 μg/kg/day). Malondialdehyde (M