𝔖 Bobbio Scriptorium
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N-[3-(Trifluoro­meth­yl)phen­yl]perhydro­pyridazine-1-carboxamide

✍ Scribed by Li, Xiao-Qing ;Sun, Zu-Guang ;Du, Xiao-Hua

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
106 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis

In the title compound, C 12 H 14 F 3 N 3 O, the perhydropyridazine ring adopts a chair conformation. The amide group and the benzene ring are coplanar. Intermolecular N-HÁ Á ÁO hydrogen bonds link the molecules into a chain along the a axis.

📜 SIMILAR VOLUMES

1-[3-(Trifluoro­meth­yl)phen­yl]-3-pival
1-[3-(Trifluoro­meth­yl)phen­yl]-3-pivaloylthio­urea
✍ Shoukat, Noreen ;Khawar Rauf, M. ;Ebihara, Masahiro ;Badshah, Amin 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 130 KB

The title compound, C~13~H~15~F~3~N~2~OS, shows an intramolecular N—H...O hydrogen bond and forms intermolecular N—H...S hydrogen bonds, generating a chain.

6-[3-Phenyl-5-(trifluoro­meth­yl)pyrazol
6-[3-Phenyl-5-(trifluoro­meth­yl)pyrazol-1-yl]pyridazin-3(2H)-one
✍ Dilek, Nefise ;Güneş, Bilal ;Şahin, Ertan ;Ide, Semra ;Ünlü, Serdar 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 166 KB

This study of the title compound, C 14 H 9 F 3 N 4 O, is part of a series of structural investigations of cyclooxygenase-2 (COX-2) inhibitors containing 1,3-diarylpyrazole derivatives. The crystal structure is stabilized by intermolecular N-HÁ Á ÁO and C-HÁ Á ÁF hydrogen-bonding interactions.