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Myxovirescin analogues via macrocyclic ring–closing metathesis

✍ Scribed by Stéphane Content; Christopher J Dutton; Lee Roberts


Book ID
108477394
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
175 KB
Volume
13
Category
Article
ISSN
0960-894X

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Synthesis of macrocyclic lactams and lac
✍ William P.D. Goldring; AndréS. Hodder; Larry Weiler 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 254 KB

## A&Wrack Lactones and lactams 4-6 were synthesized from a series of acyclic dienes 1-3 via ringclosing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the UZratios compared to values from molecular mechanics calculations.