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Myotonic Dystrophy in Transgenic Mice Expressing an Expanded CUG Repeat

✍ Scribed by Mankodi, A.

Book ID
121162972
Publisher
American Association for the Advancement of Science
Year
2000
Tongue
English
Weight
658 KB
Volume
289
Category
Article
ISSN
0036-8075

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## Abstract Mental retardation is a main feature of the congenital form of myotonic dystrophy (DM1), however, the molecular mechanisms underlying the central nervous system symptoms of DM1 are poorly understood. We have established a PC12 cell line‐based model expressing the DM1 expanded CUG repeat