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Stability of an expanded trinucleotide repeat in the androgen receptor gene in transgenic mice

โœ Scribed by Bingham, Peter M.; Scott, Marion O.; Wang, Suping; McPhaul, Michael J.; Wilson, Elizabeth M.; Garbern, James Y.; Merry, Diane E.; Fischbeck, Kenneth H.


Book ID
109915175
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
607 KB
Volume
9
Category
Article
ISSN
1061-4036

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Somatic mutations at the trinucleotide r
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## Abstract Androgen and androgen receptor (AR) have long been implicated in liver carcinogenesis, especially for the male dominance feature. However, whether AR gene could occur in somatic mutations that might contribute to this process has not yet been studied. DNA sequencing and genotyping were