Myelodysplastic syndrome evolving to a mixed myeloid-lymphoid leukaemia
✍ Scribed by Dr. J. F. San Miguel; M. Gonzalez; M. C. Del Ca≁tizo; A. López-Borrasca
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 147 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0278-0232
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Acute myeloid leukaemia (AML) secondary to myelodysplastic syndrome (MDS) is characterized by poor prognosis, namely in older patients. The combination of fludarabine (F) with cytarabine (ARA-C) AE G-CSF was proven as effective in patients with poor risk AML. The efficacy and toxicity of a regimen i
Hodgkin's disease (HD) has been linked to an increase risk of second malignant neoplasms (SMN), especially non-Hodgkin's lymphoma (NHL) and acute nonlymphoblastic leukaemia (ANLL). The mutagenic property of cytotoxic therapy as well as defective immunity have been implicated as playing a major role