Myelodysplastic syndromes: Their history, evolution and relation to acute myeloid leukaemia
β Scribed by Layton, D. M. ;Mufti, G. J.
- Publisher
- Springer-Verlag
- Year
- 1986
- Weight
- 1023 KB
- Volume
- 53
- Category
- Article
- ISSN
- 1432-0584
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Acute myeloid leukaemia (AML) secondary to myelodysplastic syndrome (MDS) is characterized by poor prognosis, namely in older patients. The combination of fludarabine (F) with cytarabine (ARA-C) AE G-CSF was proven as effective in patients with poor risk AML. The efficacy and toxicity of a regimen i
One hundred eighty-eight unselected consecutive patients with "de novo" myelodysplastic syndrome (MDS) were studied cytogenetically. They were subclassified as 4 refractory anemia with ringed sideroblasts (RARS), 67 refractory anemia (RA), 58 refractory anemia with excess of blasts (RAEB), 40 RAE6 i