Myelodysplasia and leukemia syndrome with monosomy 7: A genetic perspective
β Scribed by Gilchrist, D. M. ;Friedman, J. M. ;Rogers, P. C. J. ;Creighton, S. P.
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 549 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0148-7299
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Monosomy 7 or partial deletion of the long arm of chromosome 7 is frequently described in children with myelodysplastic syndrome and acute myeloblastic leukemia. Parental origin of chromosome 7 in children with sporadic monosomy 7 has been examined very rarely. To investigate if monosomy 7 shows par
Diabetes insipidus (DI) is a rare complication of acute myelogenous leukemia (AML). Five of the six such cases described in the literature who had banded chromosomal studies performed had monosomy 7 and the sixth patient had de1(7)(q22). A further case of AML complicated by DI in whom banded chromos
## Abstract ## BACKGROUND: Abnormalities involving chromosome 7 are frequent in myelodysplastic syndrome (MDS) and suggest a poor prognosis. ## METHODS: The authors examined the hypothesis that the clinical features and survival associated with isolated deletion (del) of part of the long arm of