Mycophenolate mofetil in psoriasis
β Scribed by GODINHO, M
- Book ID
- 123449015
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 118 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0926-9959
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A woman with a long history of widespread plaque psoriasis unresponsive to and/or intolerant of phototherapy, retinoids, methotrexate and cyclosporin was successfully treated with mycophenolate mofetil. Remission was maintained on doses between 1 and 1.5 g/day for 18 months without adverse effects.
Mycophenolate mofetil (MMF) is a new immunosuppressive drug which non-competitively and reversibly blocks the de novo synthesis of guanine nucleotides required for DNA and RNA synthesis during T- and B-cell proliferation. This induces a selective inhibition of lymphocyte proliferation. Thus MMF is c