𝔖 Bobbio Scriptorium
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Mycophenolate mofetil promising in severe psoriasis

Book ID
120867528
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2001
Weight
138 KB
Volume
1286
Category
Article
ISSN
1173-8324

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Change of treatment from cyclosporin to
Change of treatment from cyclosporin to mycophenolate mofetil in severe psoriasis
✍ S.C. Davison; R. Morris-Jones; A.V. Powles; L. Fry πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 192 KB

Eight patients whose severe psoriasis was treated with long-term cyclosporin (range 2-11 years; mean 7.6 years) were changed to mycophenolate mofetil (MMF), because of nephrotoxicity in seven and hypertension and lack of efficacy in one. In five patients psoriasis control significantly deteriorated

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Widespread plaque psoriasis responsive to mycophenolate mofetil
✍ David W Tong; Brien K Walder πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 50 KB

A woman with a long history of widespread plaque psoriasis unresponsive to and/or intolerant of phototherapy, retinoids, methotrexate and cyclosporin was successfully treated with mycophenolate mofetil. Remission was maintained on doses between 1 and 1.5 g/day for 18 months without adverse effects.

Psoriasis vulgaris treated successfully
Psoriasis vulgaris treated successfully with mycophenolate mofetil
✍ Haufs; Beissert; Grabbe; SchÜtte; Luger πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 290 KB

Mycophenolate mofetil (MMF) is a new immunosuppressive drug which non-competitively and reversibly blocks the de novo synthesis of guanine nucleotides required for DNA and RNA synthesis during T- and B-cell proliferation. This induces a selective inhibition of lymphocyte proliferation. Thus MMF is c