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Mutator phenotype in cancer: Origin and consequences

โœ Scribed by Lawrence A. Loeb


Book ID
113900483
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
98 KB
Volume
20
Category
Article
ISSN
1044-579X

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Mutator phenotype in cancer: Timing and
โœ Jason H. Bielas; Lawrence A. Loeb ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 189 KB

## Abstract Normal human cells replicate their DNA with exceptional accuracy. During every division cycle, each daughter cell receives a full and accurate complement of genetic information. It has been estimated that approximately one error occurs during DNA replication for each 10^9^ to 10^10^ nuc