On genetic information uncertainty and the mutator phenotype in cancer
β Scribed by Jason Yongsheng Chan
- Book ID
- 113494366
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 572 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0303-2647
No coin nor oath required. For personal study only.
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A subset of sporadic gastric cancers (GC) exhibits microsatellite instability (MSI). To define the precise role of MSI in GC, a total of 100 patients with sporadic GC were classified into three groups, i.e., high-frequency MSI (MSI-H), low-frequency MSI (MSI-L), and microsatellite stable (MSS), base
## Abstract Index cases from a clinically relevant cohort of 102 Spanish families with at least 3 cases of breast and/or ovarian cancer (at least 1 case diagnosed before age 50) in the same lineage were screened for germline mutations in the entire coding sequence and intron boundaries of the breas