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Mutations within the E2 and NS5A protein in patients infected with hepatitis C virus type 3A and correlation with treatment response

✍ Scribed by Sarrazin, Christoph; Kornetzky, Ilka; Ruester, Brigitte; Lee, Jung H.; Kronenberger, Bernd; Bruch, Katharina; Roth, W. Kurt; Zeuzem, Stefan


Book ID
122051954
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
181 KB
Volume
118
Category
Article
ISSN
0016-5085

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Mutations in the E2 and NS5A regions in
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## Abstract Heterogeneity of subgenomic regions of hepatitis C virus (HCV) may be associated with response to interferon (IFN) therapy. The amino acid sequences of the PKR/eIF‐2Ξ± phosphorylation homology domain (pePHD), IFN sensitivity determining region (ISDR), PKR binding domain (PKRBD), and vari