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Mutations within the E2 and NS5A protein in patients infected with hepatitis C virus type 3a and correlation with treatment response

✍ Scribed by Christoph Sarrazin; Ilka Kornetzky; Brigitte Rüster; Jung-Hun Lee; Bernd Kronenberger; Katharina Bruch; W. Kurt Roth; Stefan Zeuzem

Book ID
111721261
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
253 KB
Volume
31
Category
Article
ISSN
0270-9139

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A part of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) amino acid sequence, designated as an interferon (IFN)-sensitive determining region (ISDR), has been shown to be correlated with a response to IFN in Japanese patients. We have shown previously that the presence of NS5A antibodies