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Mutations of KRAS and BRAF in Primary and Matched Metastatic Sites of Colorectal Cancer

✍ Scribed by Artale, S.; Sartore-Bianchi, A.; Veronese, S. M.; Gambi, V.; Sarnataro, C. S.; Gambacorta, M.; Lauricella, C.; Siena, S.

Book ID
127254256
Publisher
American Society of Clinical Oncology
Year
2008
Tongue
English
Weight
68 KB
Volume
26
Category
Article
ISSN
0732-183X

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## Abstract Mutational analysis of __KRAS__ codons 12 and 13 is standard for patients with metastatic colorectal cancer since mutations in these codons predict lack of response to anti‐EGFR therapies. However, even among patients whose tumors are wildtype for __KRAS__ codons 12 and 13, only a subse