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MUTATIONS OF EPIDERMAL GROWTH FACTOR RECEPTOR IN HORMONE-SENSITIVE AND REFRACTORY PROSTATE CANCERS

✍ Scribed by Y.D. Choi; N.H. Cho; K. Park; J.S. Lee

Book ID: 118647563
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 64 KB
Volume: 5
Category: Article
ISSN: 1569-9056
DOI: 10.1016/s1569-9056(06)60408-9

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Prostate cancer is considered to be one of the most hormone-dependent human malignancies. As a key mediator of hormonal response, the androgen receptor (AR) is believed to have an important role in the progression of prostate cancer. Mutations in the coding region of the AR gene have been found in b