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MP-08.17: Mutations of epidermal growth factor receptor in hormone sensitive and refractory prostate cancers

โœ Scribed by Y.D. Choi; N.H. Cho; K. Park; K.S. Cho; S.Y. Cho; W.K. Han; M.S. Lee; J.S. Lee

Book ID
116946476
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
76 KB
Volume
68
Category
Article
ISSN
0090-4295

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Somatic mutations of epidermal growth fa
Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers
โœ Hisayuki Shigematsu; Adi F. Gazdar ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 540 KB

Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene in lung cancers have generated enormous interest, because they predict for sensitivity to TK inhibitors (TKIs). While mutational status is of great importance in determining response to TKIs, it