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Mutations in T cell Receptor ζ Chain mRNA of Peripheral T cells from Systemic Lupus Erythematosus Patients

✍ Scribed by Kensei Tsuzaka; Tsutomu Takeuchi; Natsuko Onoda; Ming Pang; Tohru Abe

Book ID: 115621588
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 202 KB
Volume: 11
Category: Article
ISSN: 0896-8411
DOI: 10.1006/jaut.1998.0223

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## Objective. T cells from patients with systemic lupus erythematosus (SLE ) display antigen receptormediated signaling aberrations associated with defective T cell receptor (TCR) chain protein and messenger RNA (mRNA) expression. This study was undertaken to explore the possibility that coding-re