๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Mutational Analysis of the Nucleotide Binding Domain of the Mismatch Repair Enzyme hMSH-2

โœ Scribed by Adrian Whitehouse; Rekha Parmar; Jayne Deeble; Graham R. Taylor; Simon E.V. Phillips; David M. Meredith; Alexander F. Markham


Book ID
115579426
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
174 KB
Volume
229
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Mutation of the mismatch repair gene hMS
โœ Lauretta Levati; Giancarlo Marra; Teresa Lettieri; Stefania D'Atri; Patrizia Ver ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 186 KB ๐Ÿ‘ 2 views

Cell killing by monofunctional methylating agents is due mainly to the formation of adducts at the O 6 position of guanine. These methyl adducts are removed from DNA by the O 6 -alkylguanine DNA alkyltransferase (OGAT). The mechanism by which O 6 -methylguanine (O 6 meG) induces cell death in OGAT-d