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Mutational Analysis of STK11 h Gene in Ovarian Carcinomas

✍ Scribed by Nishioka, Yoshihiro ;Kobayashi, Kanji ;Sagae, Satoru ;Sugimura, Masaki ;Ishioka, Shinichi ;Nagata, Masami ;Terasawa, Katuhiko ;Tokino, Takashi ;Kudo, Ryuichi

Book ID: 108581769
Publisher: Wiley (Blackwell Publishing)
Year: 1999
Tongue: English
Weight: 224 KB
Volume: 90
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1999.tb00793.x

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## Abstract The putative tumour suppressor gene __EP300__ is located on chromosome 22q13 which is a region showing frequent loss of heterozygosity (LOH) in colon, breast and ovarian cancers. We analysed 203 human breast, colon and ovarian primary tumours and cell lines for somatic mutations in __EP