Mutational analysis of caspase genes in prostate carcinomas
โ Scribed by MIN SUNG KIM; SANG WOOK PARK; YOO RI KIM; JI YOUL LEE; HYEON WOO LIM; SANG YONG SONG; NAM JIN YOO; SUG HYUNG LEE
- Book ID
- 109344025
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 121 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0365-5555
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## Background: Trka, the high affinity, tyrosine kinase receptor for nerve growth factor (ngf) has been implicated as an oncogene in several neoplasms. in prostate cancer, inhibitors of the ngf/trka signal pathway results in tumor growth inhibition. in contrast, inhibition of this trk pathway in th
Latent carcinomas of the prostate, discovered at autopsy in men with no prior treatment for prostatic disease, were studied for ras proto-oncogene mutations. Subjects included 2 I Japanese, I 5 U.S. whites, I 5 US. blacks, 20 Hawaiian Japanese and 10 Colombians. PCR and sequence-specific oligonucleo