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Mutational analysis and clinical correlation of metastatic colorectal cancer

โœ Scribed by Russo, Andrea L.; Borger, Darrell R.; Szymonifka, Jackie; Ryan, David P.; Wo, Jennifer Y.; Blaszkowsky, Lawrence S.; Kwak, Eunice L.; Allen, Jill N.; Wadlow, Raymond C.; Zhu, Andrew X.; Murphy, Janet E.; Faris, Jason E.; Dias-Santagata, Dora; Haigis, Kevin M.; Ellisen, Leif W.; Iafrate, Anthony J.; Hong, Theodore S.


Book ID
124165868
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
192 KB
Volume
120
Category
Article
ISSN
0008-543X

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Background: Identifying predictive biomarkers is important to optimally treat patients. This analysis evaluated the association of K-ras, BRAF, and PIK3CA gene mutations with tumor resistance to panitumumab alone. Patients and Methods: From 3 phase II panitumumab metastatic colorectal cancer (mCRC)