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Association of K-ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab Alone

✍ Scribed by Daniel J. Freeman; Todd Juan; Maureen Reiner; J. Randolph Hecht; Neal J. Meropol; Jordan Berlin; Edith Mitchell; Ildiko Sarosi; Robert Radinsky; Rafael G. Amado

Book ID
119935143
Publisher
CIG Media Group, LP.
Year
2008
Tongue
English
Weight
502 KB
Volume
7
Category
Article
ISSN
1533-0028

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Association of K-ras Mutational Status a
Association of K-ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab Alone
✍ Daniel J. Freeman; Todd Juan; Maureen Reiner; J. Randolph Hecht; Neal J. Meropol πŸ“‚ Article πŸ“… 2008 πŸ› CIG Media Group, LP. 🌐 English βš– 502 KB

Background: Identifying predictive biomarkers is important to optimally treat patients. This analysis evaluated the association of K-ras, BRAF, and PIK3CA gene mutations with tumor resistance to panitumumab alone. Patients and Methods: From 3 phase II panitumumab metastatic colorectal cancer (mCRC)