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7LB Analysis of KRAS mutations in patients with metastatic colorectal cancer receiving panitumumab monotherapy

✍ Scribed by R.G. Amado; M. Wolf; D. Freeman; M. Peeters; E. Van Cutsem; S. Siena; S. Suggs; S. Patterson; D. Chang


Book ID
118624943
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
38 KB
Volume
5
Category
Article
ISSN
1359-6349

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Association of K-ras Mutational Status a
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Background: Identifying predictive biomarkers is important to optimally treat patients. This analysis evaluated the association of K-ras, BRAF, and PIK3CA gene mutations with tumor resistance to panitumumab alone. Patients and Methods: From 3 phase II panitumumab metastatic colorectal cancer (mCRC)