𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

✍ Scribed by Citron, Martin; Oltersdorf, Tilman; Haass, Christian; McConlogue, Lisa; Hung, Albert Y.; Seubert, Peter; Vigo-Pelfrey, Carmen; Lieberburg, Ivan; Selkoe, Dennis J.


Book ID
109782743
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
414 KB
Volume
360
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Increasing neurite outgrowth capacity of
✍ Olga Salinero; M. Teresa Moreno-Flores; Francisco Wandosell 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 306 KB 👁 1 views

Progressive cerebral deposition of ␤-amyloid peptide either in blood vessels or around neurites is one of the most important features of Alzheimer's disease (AD). The ␤-peptide, known as A␤ or A4, is produced by proteolytic cleavage of the amyloid precursor protein (APP). Two APP processing pathways

β-Amyloid precursor protein of Alzheimer
✍ M. Mizuguchi; K. Ikeda; Seung U. Kim 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 866 KB

The production of P-amyloid precursor protein (PAPP) in cultured oligodendrocytes isolated from adult bovine brains was examined by immunohistochemistry and immunoblotting. Immunostaining of oligodendrocytes with antibodies specific for the carboxy terminus of p APP demonstrated positive immunoreact