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Mutation analysis of theBRCA1gene in Japanese patients with sporadic ovarian cancer

โœ Scribed by Shinichi Shibuya; Yoichi Aoki; H. Aida; Takumi Kurabayashi; Koichi Takakuwa; H. Nagata; M. Sekine; K. Kashima; H. J. Wu; K. Tanaka


Publisher
Springer
Year
1999
Tongue
English
Weight
155 KB
Volume
4
Category
Article
ISSN
1341-9625

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Predisposing germline mutations in the BRCAl gene were identified recently in families with 17qlinked breast and ovarian cancers. Using single-strand conformation polymorphism (SSCP) analysis, we examined primary breast cancers for mutations in coding exons of BRCAl in a panel of 103 patients, of wh