✦ LIBER ✦

Identification and evaluation of 55 genetic variations in theBRCA1and theBRCA2genes of patients from 50 Japanese breast cancer families

✍ Scribed by Masanori Kawahara; Masato Sakayori; Kazuko Shiraishi; Tadashi Nomizu; Motohiro Takeda; Rikiya Abe; Noriaki Ohuchi; Seiichi Takenoshita; Chikashi Ishioka

Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 172 KB
Volume: 49
Category: Article
ISSN: 1435-232X
DOI: 10.1007/s10038-004-0160-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A mutation analysis of theBRCA1gene in 1

A mutation analysis of theBRCA1gene in 140 families from southeast France with a history of breast and/or ovarian cancer

✍ Philippe Rostagno; Jeanine Gioanni; Eliane Garino; Pierre Vallino; Moise Namer; 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 200 KB

Prevalence of five previously reported a

Prevalence of five previously reported and recurrent BRCA1 genetic rearrangement mutations in 20,000 patients from hereditary breast/ovarian cancer families

✍ Brant C. Hendrickson; Thaddeus Judkins; Benjamin D. Ward; Kristilyn Eliason; Ami 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB

## Abstract Many rearrangement mutations in the __BRCA1__ gene have been identified. It is becoming clear that some of these mutations are prevalent, and therefore their detection is necessary in order for clinical genetic tests to have high sensitivity. Published information on particular rearrang

Mutation analysis of the BRCA1 and BRCA2

Mutation analysis of the BRCA1 and BRCA2 genes results in the identification of novel and recurrent mutations in 6/16 Flemish families with breast and/or ovarian cancer but not in 12 sporadic patients with early-onset disease

✍ Kathleen Claes; Eva Machackova; Michel De Vos; Geert Mortier; Anne De Paepe; Lud 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 41 KB 👁 2 views

Germline mutations within the adenomatous polyposis coli (APC) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations within thi