✦ LIBER ✦

Mutation analysis of the WT1 gene in sporadic childhood leukaemia

✍ Scribed by Algar, E; Blackburn, D; Kromykh, T; Taylor, G; Smith, P

Book ID: 110053385
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 69 KB
Volume: 11
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2400521

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Analysis of ras gene mutations in childh

Analysis of ras gene mutations in childhood myeloid leukaemia

✍ Christine Farr; Robert Gill; Fay Katz; Barbara Gibbons; Christopher J. Marshall 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 496 KB

Mutations of the WT1 gene in childhood n

Mutations of the WT1 gene in childhood nonlymphoid hematological malignancies

✍ Kiyoshi Miyagawa; Yasuhide Hayashi; Toshikatsu Fukuda; Kinuko Mitani; Hisamaru H 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB 👁 2 views

The Wilms' tumor gene WT1, whose loss of function accounts for the genesis of about 10% of Wilms' tumors, is expressed in hematopoietic stem cells and leukemia. By analogy with the relationship between the kidney stem cell and Wilms' tumor, it is probable that WT1 is mutated in leukemia. WT1 mutatio

The clinical relevance of Wilms Tumour 1

The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia

✍ Carolyn Owen; Jude Fitzgibbon; Peter Paschka 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 116 KB

## Abstract Recurrent genetic aberrations are important predictors of outcome in acute myeloid leukaemia (AML). Numerous novel molecular abnormalities have been identified and investigated in recent years adding to the risk stratification and prognostication of conventional karyotyping. Mutations i

Mutation analysis of the WT1 gene in sec

Mutation analysis of the WT1 gene in secondary leukemia

✍ Takahashi, T; Yamamoto, R; Tanaka, K; Kamada, N; Miyagawa, K 📂 Article 📅 2000 🏛 Nature Publishing Group 🌐 English ⚖ 123 KB

MEN1 Gene mutation analysis of sporadic

MEN1 Gene mutation analysis of sporadic adrenocortical lesions

✍ Birgit Görtz; Jürgen Roth; Ernst J.M. Speel; Akiko Krähenmann; Ronald R. De Krij 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 432 KB 👁 2 views

To clarify the role of the MEN1 gene in the tumorigenesis of sporadic adrenocortical tumors, we performed a molecular study on 35 adrenocortical lesions including 6 hyperplasias, 19 adenomas and 10 carcinomas. Loss of heterozygosity (LOH) of the MEN1 gene was assessed by PCR using an intragenic (D11

Mutation analysis of the RECQL4 gene in

Mutation analysis of the RECQL4 gene in sporadic osteosarcomas

✍ Koichi Nishijo; Tomitaka Nakayama; Tomoki Aoyama; Takeshi Okamoto; Tatsuya Ishib 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 270 KB

## Abstract Osteosarcoma (OS) is the most prevalent malignant tumor among cases of Rothmund‐Thomson syndrome (RTS) with germline mutations of the __RECQL4__ gene, a member of the RecQ helicase family. We investigated the involvement of the __RECQL4__ gene in the development of OS unrelated to RTS.