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Mutation analysis of the putative tumor suppression gene PTEN/MMAC1 in sporadic breast cancer

✍ Scribed by Shou‐Tung Chen; Shi‐Yau Yu; Matty Tsai; Kun‐Tu Yeh; Jyh‐Chwan Wang; Min‐Chih Kao; Mu‐Ching Shih; Jan‐Gowth Chang


Book ID
110232513
Publisher
Springer US
Year
1999
Tongue
English
Weight
58 KB
Volume
55
Category
Article
ISSN
0167-6806

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Epigenetic silencing of the candidate tu
✍ Beatrix Versmold; Jörg Felsberg; Thomas Mikeska; Denise Ehrentraut; Juliane Köhl 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 362 KB 👁 2 views

## Abstract Extensive hypermethylation and consecutive transcriptional silencing of tumorsuppressor genes have been documented in multiple tumor entities including breast cancer. In a microarray based genome‐wide methylation analysis of five sporadic breast carcinomas we identified a hypermethylate