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Mutation analysis of the parkin and PINK1 genes in American Caucasian early-onset Parkinson disease families

✍ Scribed by Hao Deng; Weidong Le; Joohi Shahed; Wenjie Xie; Joseph Jankovic


Book ID
116769962
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
207 KB
Volume
430
Category
Article
ISSN
0304-3940

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## Abstract Autosomal recessive early‐onset Parkinsonism (AREP) has been associated with mutations in the __Parkin__, __PINK1__, __DJ‐1__, and __ATP13A2__ genes. We studied the prevalence of mutations in all four genes in 29 Chinese unrelated families with AREP using direct sequencing analysis and