Association between Early-Onset Parkinson's Disease and Mutations in the Parkin Gene
✍ Scribed by Lücking, Christoph B.; Dürr, Alexandra; Bonifati, Vincenzo; Vaughan, Jenny; De Michele, Giuseppe; Gasser, Thomas; Harhangi, Biswadjiet S.; Meco, Giuseppe; Denèfle, Patrice; Wood, Nicholas W.; Agid, Yves; Nicholl, D.; Breteler, M.M.B.; Oostra, B.A.; De Mari, M.; Marconi, R.; Filla, A.; Bonnet, A.-M.; Broussolle, E.; Pollak, P.; Rascol, O.; Rosier, M.; Arnould, Arnould; Brice, Alexis
- Book ID
- 120321929
- Publisher
- Massachusetts Medical Society
- Year
- 2000
- Tongue
- English
- Weight
- 132 KB
- Volume
- 342
- Category
- Article
- ISSN
- 0096-6762
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## Abstract A multiethnic series of patients with early‐onset Parkinson's disease (EOP) was studied to assess the frequency and nature of __parkin__/PARK2 gene mutations and to investigate phenotype–genotype relationships. Forty‐six EOP probands with an onset age of <45 years, and 14 affected relat