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Mutation analysis of the HFE gene in hereditary hemochromatosis

✍ Scribed by O. Kenneth; C.A. Buettner; J. Genschel; M. Steiner; H. Gerl; Werner P. Schuff; H. Lochs; H.H.J. Schmidt


Book ID
118564529
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
137 KB
Volume
34
Category
Article
ISSN
0168-8278

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Mutation analysis of the HFE gene associ
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Homozygosity for the mutation Cys282Tyr in the HFE gene has recently been identified as a cause of hereditary hemochromatosis, a disorder resulting in the inappropriate absorption of iron. Approximately 10% of Caucasians are heterozygous for this mutation; however, the gene frequency in African Amer