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Mutated focal adhesion kinase induces apoptosis in a human glioma cell line, T98G

✍ Scribed by Shinya Sakurai; Yoshiko Sonoda; Emiko Koguchi; Nobusada Shinoura; Hirofumi Hamada; Tadashi Kasahara

Book ID: 117051685
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 382 KB
Volume: 293
Category: Article
ISSN: 0006-291X
DOI: 10.1016/s0006-291x(02)00192-4

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## Abstract Neuroblastoma is the most common extracranial solid tumor of childhood. Focal adhesion kinase (FAK) is an intracellular kinase that is overexpressed in a number of human tumors including neuroblastoma, and regulates both cellular adhesion and survival. We have studied the effects of FAK