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Inhibition of focal adhesion kinase induces apoptosis in human osteosarcoma SAOS-2 cells

✍ Scribed by Wang, Jialiang; Zu, Jianing; Xu, Gongping; Zhao, Wei; Jinglong, Yan

Book ID: 121544669
Publisher: S. Karger AG
Year: 2013
Tongue: English
Weight: 281 KB
Volume: 35
Category: Article
ISSN: 1010-4283
DOI: 10.1007/s13277-013-1214-0

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## Abstract Neuroblastoma is the most common extracranial solid tumor of childhood. Focal adhesion kinase (FAK) is an intracellular kinase that is overexpressed in a number of human tumors including neuroblastoma, and regulates both cellular adhesion and survival. We have studied the effects of FAK