Antisense oligonucleotides targeting the
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Fortunato Ciardiello; Rosa Caputo; Teresa Troiani; Gaetano Borriello; Ekambar R.
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Article
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2001
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John Wiley and Sons
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French
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We have constructed a series of 22 phosphorothioate 20-mer antisense oligonucleotides directed against different regions of the human (EGFR) mRNA. Treatment with EGFR antisense oligonucleotides showed a dose-dependent inhibition of human GEO colon cancer cell growth in soft agar. Western blot analys