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Antisense oligonucleodes targeting the focal adhesion kinase inhibit proliferation, induce apoptosis and cooperate with cytotoxic drugs in human glioma cells

โœ Scribed by Zhi-Min Wu; Xian-Hou Yuan; Pu-Cha Jiang; Zhi-Qiang Li; Tao Wu


Book ID
106480436
Publisher
Springer US
Year
2005
Tongue
English
Weight
568 KB
Volume
77
Category
Article
ISSN
0167-594X

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Antisense oligonucleotides targeting the
โœ Fortunato Ciardiello; Rosa Caputo; Teresa Troiani; Gaetano Borriello; Ekambar R. ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 210 KB ๐Ÿ‘ 2 views

We have constructed a series of 22 phosphorothioate 20-mer antisense oligonucleotides directed against different regions of the human (EGFR) mRNA. Treatment with EGFR antisense oligonucleotides showed a dose-dependent inhibition of human GEO colon cancer cell growth in soft agar. Western blot analys