Insertion of the erythromycin-resistance transposon Tn551 into the Staphylococcus aureus chromosome at a site which maps between the purB and ilv loci has a pleiotrophic effect on the production of a number of extracellular proteins. Production of alpha, beta and delta hemolysin, toxic shock syndrom
MUTANTS OF STAPHYLOCOCCUS AUREUS AFFECTED IN THE REGULATION OF EXOPROTEIN SYNTHESIS
✍ Scribed by ANDERS BJÖRKLIND; STAFFAN ARVIDSON
- Book ID
- 109300617
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 274 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0378-1097
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An insertional mutant was isolated from a bovine Staphylococcus aureus strain after membrane-mating with a Streptacoccus faecalis strain carrying conjugative plasmid pCFl0 : : Tn925. This mutant, designated RC 128, showed enhanced production of cc-hemolysin and proteases and decreased production of
Insertion of the erythromycin resistance transposon Tn551 into a single site of the Staphylococcus aureus chromosome resulted in decreased production of alphatoxin, serine and metallo-proteinases and several other extracellular proteins and a simultaneous increase in the production of protein A. The