Mutagenicity test systems for the detection of chromosome aberrations in vivo
β Scribed by B. E. Matter; T. Tsuchimoto
- Publisher
- Springer-Verlag
- Year
- 1980
- Tongue
- English
- Weight
- 499 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0340-5761
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Isonicotinic acid hydrazide (INH) were given by peroral intubation to pregnant mice of strain C57BL/6Ffm on day 9 of pregnancy, INH was given in the following doses: 0, 5, 25, and 125 mg/kg solved in physiological saline. Cytogenetic analysis of homogenized embryos 6, 12, 24, and 48 h, resp., after
The effect of ENU on (A) human chromosomes from blood lymphocyte cultures in vitro, and on (B) rat and mouse bone marrow chromosomes in vivo, was investigated. Doses of 25, 50, 100 and 200 mug/ml were tested in vitro and cells with chromosome breakage were found to be dose dependent. Chromosome dama
1. Incubation of trichloroethylene, 1,1-dichloroethylene, vinylchloride, tetra-chlorocyclopentadiene, the nitroso derivatives of the pesticides Carbaryl, Prometryn, and Dodin in the presence of metabolically active mouse liver microsomes and bacteria as target cells were mutagenic, whereas tetrachlo
In more than thirty years of intensive research and development in the field of bacterial mutagenicity testing, a wide range of strains with various, genetic endpoints has become available for routine studies. Selective genetic systems of great simplicity and handiness have been developed which assa