Carcinogenic N-nitroso compounds and the
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R. Preussmann
📂
Article
📅
1984
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Springer
🌐
English
⚖ 527 KB
A short review is given on the potent and organ-specific carcinogenic effects of N-nitroso compounds. Like many other chemical carcinogens, nitrosamino compounds require activation in vivo via enzymatic alpha-hydroxylation to form alkylating agents as ultimate carcinogens. Since no epidemiological d