𝔖 Bobbio Scriptorium
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Mutagenesis in Escherichia coli lacking catalase

✍ Scribed by Nieves Abril; Carmen Pueyo


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
640 KB
Volume
15
Category
Article
ISSN
0893-6692

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Escherichia coli strains with different combinations of null mutations in the katG, katE, sodA, sodB, fpg, and mutY genes were constructed to compare their spontaneous mutation frequencies and sensitivities to various oxidants with those of bacteria solely deficient in catalase (katG katE) or cytoso

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The regulation of catabolite repression of beta-galactosidase has been studied in Escherichia coli mutants deleted for the adenyl cyclase gene (cya delta), and thus unable to synthesize cyclic AMP. It has been found that, provided a second mutation occurs either in the crp gene coding for the catabo