## Abstract The mutagenesis in phage T 7 after MMSβ, HNO~2~β, hydroxylamineβ, 5βBUdRβ, and 2βAPβtreatment in relation to host controlled functions is investigated. There was no dependence of the induction of mutations on the character of the host strains (__rec, hcr__). A back mutation system (__am
Mutagenesis in bacteriophage T 7. II. UV induced mutagenesis
β Scribed by Dr. M. Meyer; Dr. W. Witte
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 285 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0233-111X
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β¦ Synopsis
Abstract
UV induced mutagenesis of bacteriophage T 7 was investigated by using a forward mutation system (host range system) and a back mutation system (amber system). The results indicate a dependence of mutation of T 7 after UV irradiation only on the rec gene controlled functions of the bacterial host. The functions controlled by pol and uvr genes have no influence. Among other types of mutations UV irradiation leads to transitions from AT to GC.
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