✦ LIBER ✦

REV7, a new gene concerned with UV mutagenesis in yeast

✍ Scribed by Lawrence, Christopher W. ;Das, Goutam ;Christensen, Roshan B.

Publisher: Springer
Year: 1985
Tongue: English
Weight: 645 KB
Volume: 200
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00383316

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✦ Synopsis

Three allelic mutations of a new yeast gene, which we have named REV7, have been isolated by testing 313 methyl methane sulfonate sensitive mutants for UV-induced reversion of a lys2 allele. Rev7 mutants are markedly deficient with respect to UV-induced reversion of lys2, are slightly sensitive to UV and appear to be in the RAD6 epistasis group for UV survival. Rev7-1, which is probably an amber mutation, does not appear to affect sporulation in homozygous diploids. The REV7 gene is located about 12 cM distal to HIS5 on chromosome IX.

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