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Muscarinic binding to mouse brain receptor sites

โœ Scribed by Yoel Kloog; Mordechai Sokolovsky


Book ID
118312942
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
466 KB
Volume
81
Category
Article
ISSN
0006-291X

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The classical (acetylcholine) binding sites of all five subtypes of muscarinic receptors are known to be subject to allosteric regulation by a variety of small molecules. The hallmarks of such modulation in binding assays are that the allosteric ligands can alter both the affinities and the rates of