Allosteric binding sites on muscarinic r
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John Ellis
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Article
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1997
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John Wiley and Sons
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English
β 133 KB
The classical (acetylcholine) binding sites of all five subtypes of muscarinic receptors are known to be subject to allosteric regulation by a variety of small molecules. The hallmarks of such modulation in binding assays are that the allosteric ligands can alter both the affinities and the rates of